Evusheld is not a vaccine
Nguyen Hong Vu – Hope City Research Institute, California, USA – Purple Ribbon Scientific Advisor – said that usually vaccines containing viral antigens can help the body recognize the real virus. Evusheld does not contain the SARS-CoV-2 viral antigen but contains antibodies to recognize the virus. The two antibodies are tixagevimab and cilgavimab. The two antibodies were injected simultaneously in two different places with a volume of 1.5 ml, so they had to be injected into a large muscle area for easy absorption. The injection site will be on the buttocks.
Normally, the SARS-Cov-2 virus uses spikes on the surface of the S protein to interact with surface receptors on our cells. This interaction helps the virus to attack the cell. When injecting Evuseld, antibodies attach to the viral spikes to prevent the virus from interacting with human cells, preventing the virus from infecting the body.
The effectiveness of Evusheld is similar to the vaccine we use, it helps reduce the spread of the virus, so many people think that Evusheld is a super vaccine. However, Dr. Vu confirmed that Evusheld is not a vaccine, it is a passive immune system, its mechanism of action is similar to that of children receiving antibodies from their mothers. The vaccines currently in use produce antibodies to prevent the virus, which are made from inside the cells of the person giving the vaccine.
Passive antibodies from Evusheld injection do not affect the two B cells and T cells in the body. These are the two cells that create the immune system, which plays an important role in preventing viruses from attacking the body and preventing viruses from causing more severe disease.
So, Evusheld is not considered a vaccineit does not affect the immune system B and T at all.
According to Dr. Vu, Evusheld has been approved by the FDA for emergencies from December 2021 with the aim of preventing infection. Evusheld is recommended when injecting for people who do not have the virus and who have not been in contact with the source of the Covid-19 infection.
world Used in people with moderate and severe immune deficiency such as HIV patients, people with blood cancer, bone marrow transplants, organ transplants…
People inject Eveheld.
Evusheld is used for subjects over 12 years of age who weigh 40 kg or more, are not infected with the virus and have not been exposed to a source of the SARS-CoV-2 virus. In addition, Evusheld can also be used as an alternative vaccine for people with a history of side effects who cannot receive the Covid-19 vaccine because the side effects can affect their lives.
Evusheld side effects
According to a recent study published in the scientific journal JAMA, Evesheld antibodies have Rooting in the body about 80 days. After 3 months, about half of the antibodies were degraded, and after 6 months, the antibodies were still protective.
Another clinical trial was conducted on 5172 people, divided into two groups with a 2:1 ratio of Evusheld injection and placebo. Observed in 83 days, it was found that in the Evusheld injection group, 8 people had Covid-19 and showed symptoms (accounting for 0.2%).
In the placebo group, 27 people had Covid-19 and had symptoms (accounting for 1%). So that the protection ability of Evusheld is 77% then followed by observation and over the next 6 months the difference is getting bigger, which is around 83%.
Regarding the side effects of Evusheld, Dr Vu said, like any other drug or vaccine, it has side effects. Through clinical trials, it was observed that common side effects such as headache accounted for 6%, fatigue accounted for 4%. In addition, people also found that the group that injected Evusheld also had side effects on the heart but not clear, but recorded 1 death after injecting Evusheld. However, the relationship between Evesheld injection and death has not been established, but it is a cause for concern.
The reason is, when conducting clinical trials of Pfizer vaccination for children aged 12 to 17 years, no myocarditis reactions were found, but during mass injections, the phenomenon of myocarditis side effects was more pronounced. .
Therefore, the above experiment with more than 5000 people still needs to be observed. If it’s injected with millions of people, what difference does it make to observe reality?
Like the Covid-19 vaccine, when a new variant changes the position of Protein S, the vaccine is no longer recognized as before and the virus “breaks through the immune defenses”, so passive antibodies to prevent Covid-19 must be used. that of the vaccine.
In a recent study, two antibodies in Evusheld were found to reduce the ability of the virus to neutralize the Omicron variant by about 12-30 times. Therefore, people are worried that if a new variant emerges, maybe the effectiveness of Evusheld will not be as good as before – said Dr. vu.
Dr Vu recommends that normal people stick to the basic dose of the vaccine as it affects the immune system, activates the body’s antibodies, and affects B and T cells. Only those who cannot be vaccinated. Vaccine or immunocompromised antibodies cannot be produced when a new vaccine is given considering Evosheld products.
at Blogtuan.info – Source: Soha.vn – Read the original article here
