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Risk of reinfection with Omicron . sub-variant

Monday, March 14 2022 08:27 (GMT+7)

According to the Ministry of Health, the BA.2 sub-variant also known as “stealth Omicron” spreads in about 100 countries, when infected with BA.1 there is still a chance of reinfection with BA.2 in the majority of young people. , has not been vaccinated.

In Hanoi, Omicron variations were recorded in 20/30 districts; the BA.2 variant accounted for 87% of all samples detected with the Omicron variant. In particular, the BA.2 sub-variant was 1.5 times more likely to spread than the BA.1 parent variant and was approximately 30% more likely to avoid immune effects from the current vaccine than the BA.1 parent variant. In Ho Chi Minh City, the Omicron variant accounted for 76% of the samples by genetic sequencing. In addition, the BA.2 variant was approximately 30% more likely to evade the immunological effects of the current vaccine than the original BA.1 variant.

Risk of reinfection with Omicron sub-variant - 1

Elderly, predisposed people should be protected from the Omicron subvariant. Photo: Thai Ha

Assoc. Prof. Dr. Tran Dac Phu, Senior Advisor to the Vietnam Center for Emergency Response to Public Health Events (Ministry of Health), said that Omicron is a strain with 36 mutations in the spike protein, helping the virus to spread. SARS-CoV-2 penetrate human cells causing rapid spread. This variant causes mild symptoms, but if not controlled will lead to an increase in infections, which can easily burden hospitals and health systems, increasing mortality. Therefore, experts recommend that people need to do 5K well because 5K helps prevent infection. “Currently the virus has not changed its transmission path, it is still transmitted through droplets. In areas where the epidemic is already very stressful, if treatment is not properly stratified, it will increase the risk of patient death,” said Dr Phu, while recommending that regions speed up vaccination. COVID-19.

To date, it is unclear whether the Omicron variant inactivates or reduces the effectiveness of the COVID-19 vaccine, but Dr. Phu said that several international studies have shown that the 3rd dose of the vaccine will have a positive effect. tension.

There are 8 symptoms of Omicron variant infection: cough, runny nose, tiredness, sore throat, headache, muscle aches, fever, sneezing. Of these, cough, runny nose, and fatigue were the most common symptoms, while fever and sneezing were the least. Then, public health experts added nausea to the list of symptoms in vaccinated people who were still infected with the Omicron variant.

Doctor Nguyen Huy Hoang, a member of an online group of doctors to support home F0 treatment, said that if a patient has been infected with the Delta strain, it is still possible to be infected with the Omicron strain within 1-2 months. “If you want to differentiate Delta or Omicron infection, BA.1 or BA.2 subvariant infection, only gene sequencing can be used to identify them,” said Dr. Hoang. However, Dr. Hoang suggests, in the current context, whether infected with Omicron or Delta, one should not be subjective and fearful. “People must remain calm and not carelessly take drugs, so they must follow official instructions from the Ministry of Health and the Ministry of Health,” said Dr Hoang.

Assoc. Prof. Dr. Nguyen Lan Hieu, Director of Hanoi Medical University Hospital, said that Omicron could be the final variant of the COVID-19 “big flood”. According to Associate Professor Nguyen Lan Hieu, it is possible that Omicron is not causing the irritation many epidemiological studies have shown, but with the current rapid rate of spread, Omicron will be a burden on the health system if there is no methodical organization.

Protect risk groups from new variants

Doctor Truong Huu Khanh, Deputy Chair of the Ho Chi Minh City Infectious Diseases Association, analyzed that viral strains with many different branches and lines are not uncommon, not only in SARS-CoV-2. “In the past, the Indian variant also had several branches, but then the Delta variant also dominated. If BA.2 spreads quickly, it will quickly overwhelm BA.1. With all types of Omicron infections, the disease is the same, whoever is vaccinated will be mild,” said Dr Khanh.

Regarding reinfection, if you have BA.1 Omicron and then you can get BA.2 again, according to Dr. Khanh, “it is possible but very rare and also in people with special conditions. According to a Danish study, the figure is only a few parts per million.” According to him, Delta infection and Omicron infection can re-infect, the rate is around 5%-10%, but the condition is also mild. “Re-infection is mild because the previous infection has also given the body a number of antibodies, of which Omicron is mild. As for Omicron infection, there is no fear re-infection of Delta, which Delta may have lost in some communities. Because the virus spreads faster, that strain will win. In my opinion, it spreads quickly but the disease is mild, does not burden resuscitation, spreads in communities that have received 3 doses of vaccine not too worrying. What needs to be done now is to protect those at risk and limit the spread of this group; ensure they have early access to the best antiretroviral drugs, monoclonal antibodies…”.

Sharing this view, Dr. Tran Dac Phu emphasized: “We must pay attention to protecting subjects who are at risk of becoming seriously ill when contracting COVID-19 such as people with underlying diseases. Limiting severe cases will help reduce the burden on the health system, especially emergency and resuscitation units, thereby reducing mortality. .

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