Liver transplant for a 5-year-old patient with severe cancer from a living human liver

D.NM, (5 years old, in Ho Chi Minh City) has malignant hepatoblastoma. In July 2021, baby M. underwent liver resection at Children’s Hospital 2 – Ho Chi Minh City. This is a rare disease in children. After surgery, the tumor continued to grow in the remaining liver.

Baby M. received 10 cycles of chemotherapy at home and abroad. However, the tumor did not respond to treatment, the tumor marker (AFP) not only did not decrease but continued to increase very high.

Computed tomography results showed that the tumor spread rapidly and extensively in both the right and left liver, not metastasized far, but the risk of progression was very bad and the prognosis for early death was not if there were no other methods of treatment. Doctors said that a liver transplant was the only option to cure the baby. The family took the baby to 108 Central Military Hospital to look for a chance to have a liver transplant.

“There is no one in the family who is eligible to donate a liver for baby M., only me is the most suitable. I am willing to donate my liver to save my grandson’s life”, Ms. G. (the patient’s biological aunt). pediatric) is a liver donor for baby M. said.

Liver transplant for a 5-year-old patient with serious cancer from a living human liver - Photo 1.

PET/CT image of the patient. Photo: BVCC.

According to Colonel Dr. Le Van Thanh – Deputy Director of the Institute of Digestive Surgery, Chairman of the Department of Hepatobiliary and Pancreatic Surgery, 108 Central Military Hospital said: “This is the youngest liver transplant with complicated and difficult pathology at the hospital. Central Military Hospital 108. The baby’s condition was weak, weighing less than 15kg due to 10 consecutive chemotherapy treatments. .”

After consultation with the hospital’s expert committee, the liver transplant team will perform laparoscopic surgery to remove 2 lower segments: II & III of the left liver from a living donor (the patient’s aunt) to perform a liver transplant for the patient. pediatric. After 7 hours, the pediatric transplant was successfully performed.

After 1 week of transplantation, baby M.’s health is stable, he is fully awake, speaks well, moves quickly, eats well, has good liver function; respiratory parameters, hemodynamics,… within normal limits. The patient was transferred to the Department of Hepatobiliary Surgery for continued treatment.

This is the third time that 108 Central Military Hospital has performed laparoscopic surgery to remove a living donor liver graft to conduct a liver transplant. Laparoscopic graft removal is one of the most difficult techniques. Currently, in the world, there are only a handful of Hepatobiliary and Liver Transplantation Centers in countries with developed medicine such as the US, Europe, Japan, and Korea that can perform laparoscopic surgery. liver transplantation from a living donor. Therefore, with the successful application of laparoscopic surgery to remove liver transplants from living donors at 108 Military Central Hospital, it has recorded a new step in the field of liver transplantation, contributing to improving the professional level of the patient. Vietnam’s organ transplant industry and opens up the prospect of saving the lives of critically ill patients, continuing to bring healthy lives to many patients.

According to Le Lien

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