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Progression of liver cancer and prognosis – Life Health

Wednesday, April 20, 2022 21:00 PM (GMT+7)

Liver cancer ranks 4th among all cancers in the world. When liver cells become cancerous, the liver cannot function properly, leading to harmful and serious effects on the body.

Liver cancer is still an obsession for many people today because the prognosis is more difficult than other cancers. More important, Liver Cancer In the early stages, there are often no symptoms.

At the late stage, when the tumor is large, some patients begin to have symptoms such as pain in the right lower ribs, fatigue, loss of appetite, weight loss…

1. Progression of liver cancer

– Initiation phase

Patients often have symptoms such as:

– Mild digestive disorders with the expression of eating less, slowly digesting or eating a lot without getting fat and losing weight.

– Patients with severe pain or slight pain in the right lower quadrant, this is an early symptom but little attention is paid to it.

– Skinny, weight loss, fatigue for unknown reasons…

– Full-blown stage

Patients with more obvious symptoms such as:

– Digestive disorders with the expression of abdominal distension, after eating, abdominal pain, flatulence, sometimes nausea and vomiting.

– The patient’s fatigue increased a lot, could not work, was thin, and lost weight quickly (5-6kg/1 month).

– Pain in the right lower quadrant, sometimes as intense as liver colic, but more often than not.

– The whole body is thin, the muscles are small, exhausted. Yellow, pale skin, the “dirty yellow” color of cancer. There may be high fever, fluctuating fever, prolonged fever… making the patient easily confused with a liver abscess.

– Possibly edema, hemorrhage, varicose veins, red hands, dry skin, hair loss (symptoms of liver failure). Sometimes abdominal pain like acute peritonitis.

2. Who needs early screening for liver cancer?

Usually divided into 2 groups of subjects with high risk of liver cancer, which can be divided into 1 group:

– Being infected with viruses and liver-related diseases, having a family history of liver cancer. Hepatitis B and hepatitis C viruses are the leading causes of primary hepatocellular carcinoma.

– Hepatitis due to autoimmune causes, may be accompanied by other autoimmune diseases such as type 1 diabetes, basedow, rheumatoid arthritis, lupus erythematosus, … non-alcoholic fatty liver. Or have other diseases but are at risk for liver cancer. The obesity, cirrhosis of the liver caused by the use of alcohol, too many stimulants…. the risk of liver cancer.

When there are symptoms such as frequent fatigue, dark yellow urine, dull pain in the liver, bleeding under the skin, you should also visit regularly for advice and screening for early detection of liver cancer.

Progression of liver cancer and prognosis - 1

Liver cancer pictures.

3. Diagnosis and differentiation of liver cancer

Clinical examination with liver cancer, doctors will assign patients to do some tests such as: Blood tests to diagnose and differentiate from inflammatory diseases.

Imaging with liver ultrasound to diagnose liver cancer is widely applied, giving a high accurate diagnosis rate. Ultrasound also shows the size and location of the tumor. However, ultrasound did not reveal the nature of the tumor.

Computed tomography (CT scaner), especially computed tomography with contrast injection has very early diagnostic value, 94% detects tumors larger than 3 cm in diameter and clearly identifies the location. u. Hepatic angiography is the correct diagnostic method for 80-90% of small tumors less than 3 cm.

Nuclear magnetic resonance imaging (MRI): has a high diagnostic accuracy (reaching an accurate diagnosis rate of 97.5% with tumors larger than 2 cm) and especially helps in detecting invasive venous lesions on the liver.

In addition, distal liver scan, chest X-ray, portal vein scan, laparoscopy, liver biopsy (can be done through laparoscopic liver biopsy or under the guidance of computed tomography) ) 90% correct diagnosis rate.

Diagnosis of liver cancer to identify the disease and also has a differential diagnosis with diseases such as:

– Liver abscess

– Benign tumor of the liver

Hemangiomas are the most common benign liver tumors.

– Liver cyst.

Other types of tumors: hypertrophic cirrhosis, adenome…

4. Prognosis and treatment of liver cancer

The prognosis of liver cancer is very poor, with studies showing that about 80% are fatal before metastasis. However, today with the advancement of medicine, the early detection of liver cancer, the treatment will be better. Patients can be cured if detected early and treated promptly.

However, many liver cancer patient usually dies in hepatic coma or exhaustion. Metastasis of liver cancer is relatively less than that of other cancers. Lymph node metastasis in 20%, usually in the liver stalk and visceral trunk. Lung metastasis 15%.

Regarding the treatment of liver cancer, depending on the patient and stage of the disease, doctors will have an appropriate treatment plan. Usually liver tumor resection is the first choice when indicated. Patients can also receive selective embolization with chemicals, alcohol injection, radiofrequency ablation of the tumor, radiation embolization, liver transplantation… Doctors will base on the stage of the disease to give recommendations. reasonable treatment.

5. Prevention of liver cancer

Liver cancer has a low prognosis compared to some other cancers. However, it is possible to reduce the risk of the disease and improve the chances of survival by detecting cancer early. Some of the following measures that may help reduce your risk include:

Limit alcohol consumption: Regularly consuming large amounts of alcohol significantly increases the risk of cirrhosis and liver cancer.

Limit tobacco use: This can help avoid liver cancer, especially in people with hepatitis B and C.

– Hepatitis B vaccine

Practice safe sex to reduce the risk of hepatitis C infection.

Also, maintain a healthy body weight: Obesity is a risk factor because fatty liver disease and cirrhosis can lead to liver cancer and diabetes. Taking care of your physical health and maintaining a moderate body weight can help reduce your risk of liver cancer.

Treating other conditions that can lead to liver cancer, such as diabetes and hemochromatosis. Treating these before they develop into liver cancer can reduce the risk of complications.

In summary: Liver cancer is quite common. The warning process of this disease is often very silent, with no clear symptoms. Often when signs of anorexia, pain in the right lower quadrant, abdominal distention, jaundice, sclera appear, weight loss, exhaustion, and biliary obstruction are present, the patient has entered late signs. liver cancer in the late stage metastases many organs in the body.

Therefore, prevention and early detection of the risk of liver cancer are very important. Accordingly, people need to be vaccinated against hepatitis B, limit alcohol, have regular health checks every 6 months, eat healthy, and do regular physical activities to prevent the risk of liver cancer.

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