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Mysterious hepatitis in children appeared in Southeast Asia, 3 children died

The children were hospitalized in the capital Jakarta with symptoms including nausea, vomiting, severe diarrhea, fever, jaundice, convulsions and loss of consciousness, the Indonesian health ministry announced.

The ministry is currently setting up a panel to determine the cause of the disease and issuing a circular to step up disease surveillance nationwide.

Mysterious hepatitis in children appeared in Southeast Asia, 3 children died - Photo 1.

Symptoms of mysterious hepatitis can include fever, fatigue, loss of appetite, nausea, vomiting, abdominal pain, dark urine, pale stools, joint pain, and jaundice.

Over the weekend, Singapore confirmed a case of acute hepatitis in a 10-month-old baby and is investigating whether the case is similar to other cases of mysterious hepatitis infection reported on worldwide or not.

According to the World Health Organization (WHO) globally, at least one other child has died from acute hepatitis and more than a dozen others have received a liver transplant after recovering from the disease.

While the cause of the disease remains unknown, investigators are studying a family of pathogens known as adenoviruses that cause a range of illnesses, including the common cold.

In the US, a surge in cases of severe hepatitis in children prompted Wisconsin health officials to issue a warning after identifying “at least four similar cases” that could lead to deaths such as: First pediatric case in the US, associated with mysterious childhood liver disease.

To date, more than 20 cases of severe hepatitis have been reported in at least seven US states, and similar cases have been reported in at least 11 countries (including the United Kingdom, the United States, Spain, and the United Kingdom). Scotland, Ireland, Israel, Japan and possibly Canada).

As of October 1, 2021, nine cases of pediatric hepatitis have been confirmed in Alabama children between the ages of 1 and 6 of unknown etiology. All 9 cases were positive for adenovirus, none of them died.

Dr. Greg DeMuri, Professor at the University of Wisconsin School of Medicine and Public Health (USA), said that adenovirus often causes gastrointestinal problems and has been known to cause hepatitis in the past. past.

According to Dr. DeMuri, not every patient with hepatitis needs to be tested for adenovirus. “However, now clinicians need to do it,” asserts Dr. DeMuri, noting that some of his colleagues are working on better diagnostic tools than transfusion blood tests. systems to pinpoint the exact cause of outbreaks.

“We need to know: Is this a mutated virus, a variant that is more infectious and more likely to cause infection in the liver, or is this just a random occurrence?” – Dr. DeMuri said.

According to the CDC, hepatitis is an inflammation of the liver due to a multitude of causes, including viral infections, alcohol use, toxins, medications, and a number of other medical conditions. Meanwhile, signs and symptoms of mysterious hepatitis can include fever, fatigue, loss of appetite, nausea, vomiting, abdominal pain, dark urine, pale stools, joint pain, and jaundice .

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