2 books to help readers better understand cancer, new therapies
Cancer has been and continues to be a disease that burdens people and the health sector globally. In 2020, Vietnam ranked 91/185 in the world in terms of incidence rate and 50/185 in mortality rate per 100,000 people due to this disease. Prof. Dr. Le Van Quang, Director of K Hospital, said that each year there are an estimated 182,000 new cancer cases and nearly 123 thousand deaths from this disease.
And learning about cancer as well as new therapies for this disease is not only the need of many patients and patients’ family members, but also those who are interested in the disease, including the medical team. medical students, medical doctors working in this specialty.
2 books “Cancer Code” and “Immunotherapy – A Breakthrough in Cancer Treatment” help readers have new understandings about cancer as well as new therapies for the disease.
Cancer code
In this book, Dr. Jason Fung takes readers through three major paradigms in understanding cancer. Cancer Model 1.0 treats cancer as a disease of excessive growth. Cancer Model 2.0 considers cancer to be a disease of random gene mutations that cause excessive growth. Both of these models increase people’s understanding of cancer, but they still have flaws.
By pursuing the mystery of cancer formation, going through the beginning of humanity, all the way to the dawn of multicellular life, Cancer Model 3.0 uncovers profound new insights. about this interesting enemy.
Accordingly, some scientists believe that the seed of cancer resides in every cell of all multicellular life. Cancer is a re-emergence, a return to the old rule, which is formed when a cell struggles to survive (transformation). Whether the seed thrives or not depends on the habitat (soil in which it is grown). The most important aspect of progression is the organism’s growth pathways – which are also nutrient-inducible pathways.
Diseases of growth are diseases of metabolism. Diseases of metabolism are diseases of growth. Cancer is a disease of evolution and ecology. While there is certainly much to be discovered, this new model of cancer represents a huge step forward.
These new insights have led to new treatments. We are finally seeing a drop in cancer incidence and mortality today, as medicine understands the benefits and limitations of screening programs. Along with realizing the dual nature of weapons that treat cancer by mass destruction of cells, scientists have improved them to provide greater accuracy. Maybe people don’t always have to kill cancer cells.
World medicine is developing weapons that affect the whole body through the immune system, which will hunt and destroy cancer cells, wherever they are hiding.
Immunotherapy – Breakthrough in cancer treatment
In this book, through fascinating stories, author Charles Graeber recounts the journey spanning from the late 19th century to the present day of many generations of scientists to solve the mystery: why the system The human immune system does not destroy cancer cells like many foreign cells from other diseases.
As it turns out, the answer to that question stems from a series of tricks that cancer has evolved to turn off normal immune responses – tricks that scientists have only recently discovered and learned to do. to beat recently. This was the moment that many are calling cancer’s “penicillin moment,” a revolutionary discovery in our understanding of cancer and how to defeat it.
For a long time, immunotherapy has always been the estranged child in the field of cancer treatment. Generations of cancer immunologists had to endure years of failure and skepticism over the years, until they gradually proved the science and effectiveness of this method within a few years. In the past decade, leading to the massive investment of many organizations and companies in the research and development of anti-cancer drugs based on immunotherapy.
Seven years after the first checkpoint inhibitor was approved, by June 2018, 940 new cancer immunotherapy drugs had been tested in half a million cancer patients in clinical institutions. In addition, 1,094 other new drugs are in the preclinical stage in laboratories. Meanwhile, the number of trials to test the synergistic efficacy of combined immunotherapies is much larger.
Three years ago, the price for Yvervoy- the FDA-approved checkpoint inhibitor CLTA-4 antagonist for the treatment of metastatic melanoma was $120,000 (equivalent to VND2.8 billion) for the first round of treatment. four courses of treatment. Keytruda, Merck’s anti-PD-1 drug for advanced melanoma, costs $150,000 for a year-long course of treatment. The fact that more and more organizations and businesses are involved in the research and development of anti-cancer drugs on the mechanism of affecting the body’s immune system brings more competition, helping to fight many types of cancer. more affordable, while helping to reduce costs and increase access to this advanced treatment for more patients.
And the book “Immunotherapy: A Breakthrough in Cancer Treatment” author Charles Graeber rewrites the incredible discovery of scientists in unleashing the human immune system to fight off cancer. On the contrary, it can even cure cancer, is a book that should be read by everyone doing biomedical research, doctors, medical staff working in the field of cancer treatment. The book is also a fascinating document, bringing hope to cancer patients.
at Blogtuan.info – Source: cafebiz.vn – Read the original article here
