Smart sensor device reveals physiological response after vaccination against COVID-19

A recent health study by researchers at the Scripp Research Institute (USA) has shown how data is collected from wearable sensor devices, such as smartwatches or bracelets. health monitoring hand, can monitor the user’s physiological response after vaccination against COVID-19.

The study, published in the journal npj Digital Medicine, analyzed data from sensors that tracked the sleep, activity and heart rate of more than 5,600 people. The researchers gathered data from a larger project called Digital Device Engagement and Tracking for Early Treatment and Control (DETECT) launched in March 2020 in response to with the rapid spread of the SARS-CoV-2 virus that causes the disease COVID-19.

DETECT is a mobile app research platform that allows participants to share physiological and behavioral data collected via a fitness band or smartwatch, as well as update symptoms, test results and vaccination status manually.

To determine if the wearable could uncover biomarkers of post-vaccination immune responses, the scientists analyzed DETECT sensor data from two weeks before and after each injection. They compared the post-vaccination changes to the participants’ resting heart rate, sleep, and activity levels against baseline.

The results showed that the average resting heart rate of the study participants increased significantly the day after vaccination, peaked 2 days after vaccination and returned to normal 4 days after the first dose and 6 days after the vaccination. second nose. Heart rate increase was stronger at rest after the second dose of Moderna’s vaccine, compared with the Pfizer/BioNTech vaccine, and was more pronounced in younger people. In addition, the study also found that prior exposure to COVID-19 was associated with a significant increase in resting heart rate after the first dose of the vaccine compared with those without.

The results also showed that women had larger changes than men in resting heart rate five days after the first dose of the vaccine. In addition, those younger than 40 had higher resting heart rate variability than older adults, but only after the second shot. Activity levels and sleep seem to be affected the least by the first dose of the vaccine. However, immediately after the second dose, activity levels dropped significantly and sleep increased relative to baseline.

Dr. Giorgio Quer, Director of Artificial Intelligence at Scripps Research Institute, and lead author of the study, said the findings are the first step towards “meaing” the physiological response to vaccination. in people wearing smart sensor devices. Understanding the physiological signals in the period around vaccination can help scientists better understand how the body changes after vaccination against COVID-19 between people, as well as post-vaccination responses. in each individual. The individual physiological changes resulting from the initial post-vaccination immune response may provide useful guidelines for future vaccine development to optimize the efficacy and safety of vaccines. this. This also allows health professionals to develop a more precise vaccination schedule tailored to each individual.

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