In Superman #180 in 2002, when Superman met Dracula. And this vampire tried to transform Superman into one of them. Since magic is Superman’s weakness, Dracula actually pierced Superman’s skin.
However, Superman is now unharmed, because Superman is a living solar battery. His cells are constantly storing photons from the Earth’s “golden sun”, so Superman’s cells contain an enormous amount of energy derived from pure daylight.
When a vampire bites Superman, it’s basically biting the sun, and this will lead to a bad outcome for Dracula. Sunlight is the antidote to vampires and so Dracula bites and sucks Superman’s blood, this energy will burn Dracula from within and turn him to ashes.