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“3 noses” against Covid-19 for a long time-Life health

Friday, March 25, 2022 19:00 PM (GMT+7)

The Australian study found that although some part of the immune response acquired by contracting Covid-19, or by vaccination, weakens over time, the T cell count is still 10 times higher after 1 year, if compared with people who have never been ill or injected.

Work carried out by the Peter Doherty Institute for Infection and Immunity (referred to as the Doherty Institute, Melbourne, Australia), demonstrated the role of cellular immunity against Covid-19 after illness or vaccination.

Prior to this, many studies showed that the amount of antibodies acquired from vaccines or diseases often decreases over time, raising concerns that the pandemic is difficult to end or we will have to get injections again and again. But more and more work shows that with prior infection and the right number of shots, we can get long-term protection through cellular immunity.

Antibodies decrease, others increase unexpectedly: "3 nose"  long-term fight against Covid-19 - 1

The Covid-19 vaccine not only produces antibodies, but also strongly activates T cells to help create long-term, sustainable cellular immunity (Illustration from the Internet)

The Medical Xpress newspaper quoted Dr Jennifer Juno of the University of Melbourne, a research fellow at the Doherty Institute, the lead author of the paper, as saying that although the immune response “shrinks” immediately after contracting Covid-19 and recovered, but T-cell activity stabilized after 6 months and maintained levels after 15 months.

Similar reactions have also been observed in people who received the full number of basic doses of the Covid-19 vaccine.

Overall, having had an immune response triggered by a disease or vaccination resulted in a 10-fold higher T-cell count after 1 year compared with people who had never been ill or vaccinated.

If people who already have the disease are vaccinated again, the T-cell levels are boosted up to 30 times higher than before.

Similarly, in humans given a booster dose (usually a 3rd dose), the injection also produced an “amazing” response in reactivating the T-cell response, bringing the level of cellular immunity to a higher level. go up again just like the stage just finished the basic injections.

This immunity also has the same value as immunity thanks to the abundance of antibodies after vaccination: it helps to reduce the risk of disease and reduce the severity of the disease if it is caught.

T cells are an important type of immune cell in the body. While B cells are responsible for the production of antibodies that recognize SARS-CoV-2then T cells play an important role in aiding the development of the B cell response. Without the help of T cells, B cells would not be able to make the large amount of antibodies possible. binds to viruses and blocks them.

The information has just been published in the journal Nature Immunology.

Previously, a study by the University of New South Wales (Sydney – Australia) also showed that 3 doses are the ideal number for maximum and long-term immune system activation; The fourth dose will only be needed for special people, for example people who are immunocompromised due to disease or age.

In Vietnam, “nose 3” is also classified into 2 types: booster shots in healthy people; but it is only an additional dose in immunocompromised people, not a booster, so this group may need a fourth dose as a booster.

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